I-Mab Accelerates Clinical Development of Anti-CD47 Monoclonal Antibody Lemzoparlimab in the US and China

SHANGHAI and GAITHERSBURG, Md., Dec. 4, 2020 /PRNewswire/ — I-Mab (the “Company”) (Nasdaq: IMAB), a clinical stage biopharmaceutical company committed to the discovery, development and commercialization of novel or highly differentiated biologics, today announced the advancement of clinical development of the highly differentiated anti-CD47 monoclonal antibody lemzoparlimab (also known as TJC4) in the US and China, achieving milestones as planned. The Company is progressing its US combination trial (NCT03934814), studying lemzoparlimab in combination with Rituxan® and Keytruda® in dose expansion cohorts in non-Hodgkin lymphoma (NHL) and advanced solid tumors, respectively. The combination study with Rituxan® will enroll NHL patients from both the US and China. Topline results from this study are expected next year.

I-MAB Logo (PRNewsfoto/I-Mab Biopharma)

“The results from early investigational studies support the notion that lemzoparlimab is a differentiated CD47 antibody therapy for cancers that remains among the most common causes of death around the world,” said Jordan Berlin

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China aims to shake US grip on chip design tools

Veteran engineers and high-level executives are leaving top US chip design toolmakers for Chinese rivals as Beijing seeks to break America’s near monopoly on this key segment of the semiconductor industry.

Three Chinese start-ups established since September last year were founded by or have hired executives and engineers from Synopsys and Cadence Design Systems of the US, the world’s two biggest makers of electronic design automation (EDA) tools, as such software is known.

The start-ups include Nanjing-based X-Epic, Shanghai Hejian Industrial Software and Hefei-based Advanced Manufacturing EDA Co, or Amedac, in which Synopsys owns a stake.

The push to recruit US chip tool talent comes as Washington’s crackdown on Huawei Technologies exposes key weaknesses in China’s chipmaking ecosystem, including in EDA tools, which are used to design integrated circuits, printed circuit boards and other electronic systems.

The US has long dominated the segment, with Synopsys, Cadence, Mentor Graphics and Ansys

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China Drafts Rules on Mobile Apps’ Collection of Personal Data | Technology News

(Reuters) – China unveiled draft guidelines on Tuesday seeking to limit the scope of mobile apps’ collection of personal data in the latest attempt to curb the sprawling technology sector.

The set of draft rules published by the Cyberspace Administration of China covers 38 types of apps from online shopping and instant messaging to ride-hailing and bike sharing.

China has increased scrutiny of its technology sector in recent weeks, last month drafting anti-monopoly rules for tech firms.

It has also expressed concerns about data protection and consumer rights, while authorities have on a number of occasions ordered apps to be suspended for mishandling user information.

“In recent years, mobile internet applications have been widely used and have played an important role in promoting economic and social development and serving people’s livelihoods,” the cyber administration said in a statement.

“At the same time, it is common for apps to collect …

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China gets tough on firms over single-use plastics



a pile of stuffed animals: Recycling in China


© Getty Images
Recycling in China

China is forcing restaurants, e-commerce platforms and delivery services to report their use of single-use plastics.

The Ministry of Commerce said it had established a nationwide system for retailers to report their plastic consumption.

The Ministry’s proposal is part of a wider push to deal with China’s huge waste problem.

The rise in home food deliveries has also caused volumes to surge.

In September, the ministry said single-use plastic bags and eating utensils would be banned from major cities by the end of the year, while single-use straws would be banned nationwide.

A new “solid waste law” also came into effect in September, increasing fines tenfold for those who break rules.

The new law also mandated the construction of new recycling infrastructure.

Plastic pollution

Wang Wang, chairman of the China Scrap Plastic Association, told Reuters the bans would “only resolve the most visible types

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The 2020 World Industrial Design Conference & China Outstanding Industrial Design Award Ceremony held in Yantai

YANTAI, China, Nov. 30, 2020 /PRNewswire/ — On November 25, the 2020 World Industrial Design Conference (WIDC 2020) & the China Outstanding Industrial Design (CEID) Award Ceremony took place in Yantai, Shandong, according to the Information Office of the Yantai Municipal People’s Government.

WIDC 2020 City Light Show

 

WIDC 2020 Opening Ceremony

 

WIDC 2020 Exterior View of Main Venue

 

WIDC 2020 CEID Award Exhibition

 

The China Outstanding Industrial Design (CEID) Award Ceremony

With the support of the United Nations Industrial Development Organization (UNIDO), the conference was jointly hosted by the Ministry of Industry and Information Technology (MIIT) and the Shandong Provincial People’s Government. It was organized by the Shandong Province Department of Industry and Information Technology, the Yantai Municipal People’s Government, and the China Industrial Design Association.

With the theme ‘Intelligent Design, Road to the Future’, the conference collaborated with the Global Design Industry Organization (GDIO) as well as design associations, enterprises, institutions, universities and innovation leaders from more than 40 countries around the world. The innovative 3I integration initiative — Idea, Intelligence & Industrial

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Australia demands apology from China after fake image posted on social media

By Kirsty Needham



a man wearing a suit and tie: Australian Prime Minister Scott Morrison visits Tokyo


© Reuters/ISSEI KATO
Australian Prime Minister Scott Morrison visits Tokyo

SYDNEY (Reuters) – Australia’s prime minister said a fake image of an Australian soldier posted on a Chinese official’s Twitter account was “truly repugnant” and Canberra was demanding it be taken down, amid deteriorating relations between the two countries.

Scott Morrison called a media briefing to condemn the posting of the image, which depicted an Australian soldier holding a knife to the throat of an Afghan child, and said Canberra was seeking an apology from Beijing.

The Australian government has asked Twitter to remove the tweet, posted on Monday by China’s foreign ministry spokesman Zhao Lijian, Morrison said.

“It is utterly outrageous and cannot be justified on any basis,” Morrison said. “The Chinese government should be utterly ashamed of this post. It diminishes them in the world’s eyes.”

Australia’s relationship with China has deteriorated since Canberra

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Alibaba Health: Leading Internet Healthcare Company In China (OTCMKTS:ALBHF)

Elevator Pitch

I assign a Neutral rating to Chinese internet healthcare company Alibaba Health Information Technology Limited (OTCPK:ALBHF, 241:HK).

The support and backing of its parent and controlling shareholder Alibaba Group (BABA) is Alibaba Health’s key competitive advantage. Alibaba Health benefits from a strong brand equity and low customer acquisition costs due to its association with Alibaba Group and the “Alibaba” brand. Looking ahead, Alibaba Health’s key growth opportunities are in prescription drugs and medical & healthcare services.

But there are hurdles that need to be overcome for Alibaba Health to realize the growth opportunities in prescription drugs and medical & healthcare services. It might take a while for most or all the provinces in China to implement the changes relating to reimbursements for online medical services and products to on a nation-wide basis in the country; and the conversion rate for paid medical consultation services could be potentially lower

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China Display Maker Ditches U.S. to Seek $1.8 Billion Local IPO

(Bloomberg) — Chinese flexible display maker Royole Corp. is seeking to raise as much as 12 billion yuan ($1.8 billion) in an initial public offering on Shanghai’s Star Market board after its U.S. listing plan was shelved, according to people familiar with the matter.



a close up of a computer: A Royole Corp. Flexpai smartphone sits on display during the 2019 Consumer Electronics Show (CES) in Las Vegas, Nevada, U.S., on Wednesday, Jan. 9, 2019. Dozens of companies will give presentations at the event, where attendance is expected to top 180,000, with the trade war between the U.S. and China as well as Apple's sales woes looming over the gathering.


© Bloomberg
A Royole Corp. Flexpai smartphone sits on display during the 2019 Consumer Electronics Show (CES) in Las Vegas, Nevada, U.S., on Wednesday, Jan. 9, 2019. Dozens of companies will give presentations at the event, where attendance is expected to top 180,000, with the trade war between the U.S. and China as well as Apple’s sales woes looming over the gathering.

The company plans to file the application to China’s Nasdaq-style trading venue as soon as December, said the people who asked not to be identified as the matter is not public. Royole could see its valuation rise to over $8 billion, said the people,

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Exclusive: Foxconn to shift some Apple production to Vietnam to minimise China risk

TAIPEI (Reuters) – Foxconn is moving some iPad and MacBook assembly to Vietnam from China at the request of Apple Inc, said a person with knowledge of the plan, as the U.S. firm diversifies production to minimise the impact of a Sino-U.S. trade war.

The development comes as the outgoing administration of U.S. President Donald Trump encourages U.S. firms to shift production out of China. During Trump’s tenure, the United States has targeted made-in-China electronics for higher import tariffs, and restricted supplies of components produced using U.S. technology to Chinese firms it deems a national security risk.

Taiwanese manufacturers, wary of being caught up in the tit-for-tat trade war, have moved or are considering moving some production from China to countries such as Vietnam, Mexico and India.

Foxconn is building assembly lines for Apple’s iPad tablet and MacBook laptop at its plant in Vietnam’s northeastern Bac Giang province, to come

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India import hurdles hit Apple iPhone, Xiaomi devices from China, say sources

By Sankalp Phartiyal and Aditya Kalra



logo: FILE PHOTO: The Apple logo is displayed at an event at their headquarters in Cupertino


© Reuters/STEPHEN LAM
FILE PHOTO: The Apple logo is displayed at an event at their headquarters in Cupertino

NEW DELHI (Reuters) – India’s tight control of quality clearances for electronic goods from China slowed the import of Apple’s new iPhone model last month and held up other products made by companies like Xiaomi, according to two industry sources.



a man standing in front of a sign: FILE PHOTO: Attendants are silhouetted in front of Xiaomi's logo in Beijing


© Reuters/Kim Kyung Hoon
FILE PHOTO: Attendants are silhouetted in front of Xiaomi’s logo in Beijing

Applications to the quality control agency, the Bureau of Indian Standards (BIS), typically used to be processed within 15 days, but some are now taking up to two months or longer.

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BIS started delaying approvals in August for China-made imports of devices like smartphones, smartwatches and laptops, part of the fallout from deteriorating ties with China after a border clash in June that left 20 Indian soldiers dead.

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