I-Mab Accelerates Clinical Development of Anti-CD47 Monoclonal Antibody Lemzoparlimab in the US and China

SHANGHAI and GAITHERSBURG, Md., Dec. 4, 2020 /PRNewswire/ — I-Mab (the “Company”) (Nasdaq: IMAB), a clinical stage biopharmaceutical company committed to the discovery, development and commercialization of novel or highly differentiated biologics, today announced the advancement of clinical development of the highly differentiated anti-CD47 monoclonal antibody lemzoparlimab (also known as TJC4) in the US and China, achieving milestones as planned. The Company is progressing its US combination trial (NCT03934814), studying lemzoparlimab in combination with Rituxan® and Keytruda® in dose expansion cohorts in non-Hodgkin lymphoma (NHL) and advanced solid tumors, respectively. The combination study with Rituxan® will enroll NHL patients from both the US and China. Topline results from this study are expected next year.

“The results from early investigational studies support the notion that lemzoparlimab is a differentiated CD47 antibody therapy for cancers that remains among the most common causes of death around the world,” said Jordan Berlin

Read More

CdA council puzzles over piecing together mixed-use development along Spokane River

The city of Coeur d’Alene has acquired almost 5 acres of land adjacent to an ambitious, publicly owned. mixed-use development on a prime spot near downtown and on the banks of the Spokane River.

Now it has to decide what to do with it.

That decision was the subject of a lengthy presentation and discussion at Tuesday’s City Council meeting, where council members, Mayor Steve Widmyer, an engineer enlisted to help design the development and the head of the city’s urban renewal agency, ignite CDA, discussed their options.

The possibilities on the table ranged from creating a gated community on the triangular parcel to building office, hotel or apartment towers, to constructing a mix of townhomes and houses.

Council members ultimately decided to take a couple of weeks to mull over the kind of decision usually left to private developers.

As they do so, they will have to consider a

Read More

New data supports development of colchicine for the prevention of acute respiratory distress syndrome

The MarketWatch News Department was not involved in the creation of this content.

MONTREAL, Dec 03, 2020 (GLOBE NEWSWIRE via COMTEX) —
MONTREAL, Dec. 03, 2020 (GLOBE NEWSWIRE) — TheMontreal Heart Institute (MHI) has announced that colchicine, a widely available low-cost drug, reduces acute lung injury (ALI), acute respiratory distress syndrome (ARDS) and respiratory failure in pre-clinical models1. The article reporting these results was published yesterday by the Public Library of Science ONE (PLOS ONE) 1.

“This study was designed and executed in the wake of the COVID-19 pandemic as there were no effective therapies at that time to prevent SARS-CoV-2 related lung injury and ARDS,” said Dr. Jean-Claude Tardif, Director of the MHI Research Center, Professor of Medicine at the University of Montreal, COLCORONA Principal Investigator and co-principal lead author of the study published in PLOS ONE. “In the context of COVID-19, there is an

Read More

Red Light Holland Names Internationally Renowned & Award-Winning Designer Karim Rashid as Head of Design

(MENAFN – Newsfile Corp) Red Light Holland Names Internationally Renowned & Award-Winning Designer Karim Rashid as Head of Design

Toronto, Ontario–(Newsfile Corp. – December 3, 2020) – [To enable links contact MENAFN] Red Light Holland Corp. (CSE: TRIP) (FSE: 4YX) (OTC: TRUFF) (“[To enable links contact MENAFN] Red Light Holland” or the “Company”) is pleased to name Karim Rashid – Head of Design, for the design and development of the Wisdom Truffle companion. Karim Rashid who has 1.1 million Facebook followers, 210,000 Instagram followers and 29,000 Twitter Followers, has been described by Time Magazine as the “most famous industrial designer in all the Americas”.

[To enable links contact MENAFN]

Pictured Karim Rashid
If you cannot view this image, please visit:
[To enable links contact MENAFN]

“We are thrilled to name world-renowned designer Karim Rashid, Head of Design at Red Light Holland. While focusing on our core business in the

Read More

AudioGO Self-serve Audio Advertising Platform Now Features In-app Banner Design Using Canva

The MarketWatch News Department was not involved in the creation of this content.

Today, AudioGO, the self-serve digital audio ad buying service from AdsWizz, announced an integration with Canva, the world’s fastest growing design platform. The integration enables AudioGO advertisers to easily create display ads with Canva’s graphic design platform during campaign setup, enabling anyone to complement their audio ad campaigns with professional-looking banner ads. In addition, if an advertiser does not have an audio ad, AudioGO will create one for them in under a day.

The new Canva integration comes on the heels of new behavioral targeting capability added earlier this month, making it easier than ever for audio advertisers to connect and engage with the right audiences.

“Our mantra is to make AudioGO easy to use for anyone looking to run audio campaigns of any size,” said AdsWizz CEO Alexis van de Wyer. “Our integration with Canva gives

Read More

7 Ways To Reduce Anxiety In The Home Through Design

Your physical environment plays a major role in your mood and mental well-being. Having a space that reduces anxiety is especially important as we continue to work from home as we approach the end of a turbulent 2020. Now, more than ever, architects and designers are called on to design spaces that allow people to thrive. 

Here are seven suggestions from members of the design community for a home that keeps you healthy and makes you happy.

1.  Embrace Natural Colors And Textures

“Softer neutrals with hints of color bring calm into an environment. Woods, stone, natural fibers enliven the senses,” says Suzanne Tick, Creative Director at Luum Textiles. “Tactility plays an important role as well – we all want softness – but a feeling of safety and cleanability, not sterility, is also important. Natural

Read More

Trump signs another executive order on governmental AI development

Outgoing US President Donald Trump on Thursday signed an executive order that aims to guide how federal agencies adopt artificial intelligence (AI) as part of efforts to build public trust in the government using this technology. 

The order itself directs federal agencies to be guided by nine principles when designing, developing, acquiring, and using AI. These principles emphasise that AI use by federal agencies be lawful; purposeful and performance-driven; accurate, reliable, and effective; safe, secure, and resilient; understandable; responsible and traceable; regularly monitored; transparent; and accountable. 

To implement these principles, the order directs the Office of Management and Budget to create a roadmap by the end of May 2021 for how the government will better support the use of AI. This roadmap will include a schedule for engaging with the public and timelines for finalising relevant policy guidance. 

The order also calls on agencies to continue to use voluntary consensus

Read More

Blue Pearl Software and Japan’s CM Engineering Collaborate to Improve FPGA/SoC Design Quality

Blue Pearl Software Inc., announced that it is collaborating with Japan’s CM Engineering Co. Ltd. to help Japanese companies looking to improve the quality and reliability of their FPGAs and SoCs.

SANTA CLARA, Calif. (PRWEB) December 03, 2020

Blue Pearl Software Inc., today announced that it is collaborating with Japan’s CM Engineering Co. Ltd., a wireless communication, FPGA/SoC design and verification services company, to help local Japanese companies looking to improve the quality and reliability of their FPGAs and SoCs. The collaboration includes a free Clock Domain Crossing (CDC) trial service from CM Engineering, featuring CDC analysis with Blue Pearl Software’s Visual Verification Suite™.

With the CDC trial service, CM Engineering will perform a no-cost CDC analysis using the Visual Verification Suite’s CDC analysis solution for companies who register and provide the appropriate design information. As part of the trial service, CM Engineering will deliver the CDC result summary report

Read More

China aims to shake US grip on chip design tools

Veteran engineers and high-level executives are leaving top US chip design toolmakers for Chinese rivals as Beijing seeks to break America’s near monopoly on this key segment of the semiconductor industry.

Three Chinese start-ups established since September last year were founded by or have hired executives and engineers from Synopsys and Cadence Design Systems of the US, the world’s two biggest makers of electronic design automation (EDA) tools, as such software is known.

The start-ups include Nanjing-based X-Epic, Shanghai Hejian Industrial Software and Hefei-based Advanced Manufacturing EDA Co, or Amedac, in which Synopsys owns a stake.

The push to recruit US chip tool talent comes as Washington’s crackdown on Huawei Technologies exposes key weaknesses in China’s chipmaking ecosystem, including in EDA tools, which are used to design integrated circuits, printed circuit boards and other electronic systems.

The US has long dominated the segment, with Synopsys, Cadence, Mentor Graphics and Ansys

Read More

Despite development slowdown, the state’s life science industry keeps on building

From the industry’s traditional hub in Cambridge’s Kendall Square to emerging hot spots in Fort Point and the Fenway to vast campuses in more distant locations such as the former Fort Devens, life science companies are launching a wide array of projects, fueled by investors attracted to a fast-growing industry.

“There’s just tremendous interest in investing in these sort of projects,” said John Bonnano, chief investment officer at IQHQ, a real estate firm that’s launching two major life science developments here, and earlier this month closed on a $1.7 billion fund to finance more in Boston, San Francisco, and San Diego. “There’s an awful lot of capital out there right now.”

It’s chasing a market that has only become stronger relative to other real estate sectors. Traditional office tenants now occupy about 3 million fewer square feet of space across Greater Boston than they did at the start of the

Read More